The PCCA antibody - N-terminal region (ARP33071_P050) from Aviva Systems Biology is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The PCCA antibody - N-terminal region (ARP33071_P050) has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
PCCA is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA is the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia.The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Two transcript variants encoding different isoforms have been found for this gene